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Other Medicines
When you are taking a butalbital and acetaminophen combination, it is especially important that your health care professional know if you are taking any of the following:

- Anticoagulants (b lood thinners), or
- Carbamazepine (e.g., Tegretol) or
- Contraceptives, oral (birth control pills) containing estrogen, or
- Corticosteroids (cortisone-like medicines) or
- Cortic otropin (e.g., ACTH)ˇXButalbital may make these medicines less effective

What is this Drug
Acetaminophen ispain reliever and fever reducer. Butalbital is inclass of drugs called barbiturates that slow down your central nervous system (brain and nerve impulses) causing relaxation. Caffeine i s believed to constrict dilated blood vessels that may contribute to tension headaches. Together, acetaminophen, butalbital, and caffeine - Esgic is used to relieve complex tension (muscle contraction ) headaches although precisely how it works is unknown. Acetamino phenbutalbital caffeine - Esgic may also be used for purposes other than those listed in this medication guide.

Before Using This Medicine
Older adultsˇX

- For butalbital: Certain side effects, such as confusion, excitement, or mental depression, may be especially likely to occur in elderly patients, who are usually more sensit ve than younger adults to the effects of the butalbital in this combination medicine.
- For acetaminophen: Acetaminophen has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.
- For caffeine: There is no specific information comparing use of caffeine in the elderly with use in other age groups

Symptoms of overdose
Anxiety, confusion, excitement, irritability, nervousness, restlessness, or trouble in sleeping (severe, especially with products containing caffeine) ; convulsions (seizures) (for products containin g caffeine); diarrhea, especially if occurring together with increased sweating, loss of appetite, and stomach cramps or pain; dizziness, lightheadedness, drowsiness, or weakness, (severe) ; freque nt urination (for products containing caffeine) ; hallucinations (seeing, hearing, or feeling things that are not there); increased sensitivity to touch or pain (for products containing caffeine); muscle trembling or twitching (for products containing caffeine); nausea or vomiting, sometimes with blood;

How should this medicine be used?
People who get a lot of headaches may need to take a different medicine to help prevent headaches. It is important that you follow your doctor's directions about taking the other medicine, even if you r headaches continue to occur. Headache-preventing medicines may take several weeks to start working. Even after they do start working, your headaches may not go away completely. However, your headach es should occur less often, and they should be less severe and easier to relieve than before. This will reduce the amount of headache relievers that you need. If you do not notice any improvement afte r several weeks of headache-preventing treatment, check with your doctor.

Missed Dose
Take the missed dose as soon as you remember. Do not takedouble dose of Esgic . Wait the prescribed amount of time before taking your next dose.




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