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Why is this medication prescribed?
Acetaminophen ispain reliever and fever reducer. Butalbital is inclass of drugs called barbiturates that slow down your central nervous system (brain and nerve impulses) causing relaxation. Caffeine i
s believed to constrict dilated blood vessels that may contribute to tension headaches. Together, acetaminophen, butalbital, and caffeine - Esgic is used to relieve complex tension (muscle contraction
) headaches although precisely how it works is unknown. Acetamino phenbutalbital caffeine - Esgic may also be used for purposes other than those listed in this medication guide.
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Drug Interactions
It is especially important that your health care professional know if you are taking any of the following:
- Antidepressants, tricyclic (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendi
n], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [
e.g., Surmontil]) or
- Central nervous system (CNS) depressants (medicines that often cause drowsiness)¡XThese medicines may add to the effects of butalbital and increase the chance of drowsiness
or other side effects
- Divalproex (e.g., Depakote) or
- Valproic acid (e.g., Depakene)¡XThe chance of side effects may be increased
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Missed Dose
Take the missed dose as soon as you remember. Do not takedouble dose of Esgic . Wait the prescribed amount of time before taking your next dose.
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Precautions Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For butalbital and acetaminophen combinat
ions, the following should be considered:
Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to butalbital or other barbiturates, or to acetaminophen, aspirin,
r caffeine. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
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How to Use
This medicine will relieve a headache best if you take it as soon as the headache begins. If you get warning signs of a migraine, take this medicine as soon as you are sure that the migraine is coming
. This may even stop the headache pain from occurring. Lying down in a quiet, dark room for a while after taking the medicine also helps to relieve headaches.
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Special warnings about this medication
If you think you or anyone else may have taken an overdose of this medicine, get emergency help at once. Taking an overdose of this medicine or taking alcohol or CNS depressants with this medicine may
lead to unconsciousness or possibly death. Signs of butalbital overdose include severe drowsiness, confusion, severe weakness, shortness of breath or unusually slow or troubled breathing, slurred spe
ech, staggering, and unusually slow heartbeat. Signs of severe acetaminophen poisoning may not occur until 2 to 4 days after the overdose is taken, but treatment to prevent liver damage or death must
be started within 24 hours or less after the overdose is taken.
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