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Missed Dose
Take the missed dose as soon as you remember. Do not takedouble dose of Esgic . Wait the prescribed amount of time before taking your next dose.
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Before Using This Medicine
Children¡X - For butalbital: Although barbiturates such as butalbital often cause drowsiness, some children become excited after taking them. - For acetaminophen: Acetaminophen has been
tested in children and, in effective doses, has not been shown to cause different side effects or problems than it does in adults. - For caffeine: There is no specific information comparing use o
f caffeine in children up to 12 years of age with use in other age groups. However, caffeine is not expected to cause different side effects or problems in children than it does in adults.
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Why is this drug prescribed?
Some butalbital and acetaminophen combinations also contain caffeine (KAF-een) . Caffeine may help to relieve headaches. However, caffeine can also cause physical dependence when it is used for a long
time. This may lead to withdrawal (rebound) headaches when you stop taking it. Butalbital and acetaminophen combination may also be used for other kinds of headaches or other kinds of pain a
s determined by your doctor.
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Cautions
If you think you or anyone else may have taken an overdose of this medicine, get emergency help at once. Taking an overdose of this medicine or taking alcohol or CNS depressants with this medicine may
lead to unconsciousness or possibly death. Signs of butalbital overdose include severe drowsiness, confusion, severe weakness, shortness of breath or unusually slow or troubled breathing, slurred spe
ech, staggering, and unusually slow heartbeat. Signs of severe acetaminophen poisoning may not occur until 2 to 4 days after the overdose is taken, but treatment to prevent liver damage or death must
be started within 24 hours or less after the overdose is taken.
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Significant Interactions:
It is especially important that your health care professional know if you are taking any of the following: - Antidepressants, tricyclic (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendi
n], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [
e.g., Surmontil]) or - Central nervous system (CNS) depressants (medicines that often cause drowsiness)¡XThese medicines may add to the effects of butalbital and increase the chance of drowsiness
or other side effects - Divalproex (e.g., Depakote) or - Valproic acid (e.g., Depakene)¡XThe chance of side effects may be increased
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What side effects may occur?
Although side effects from acetaminophen, butalbital, and caffeine are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away: - drowsiness -
upset stomach - vomiting - stomach pain - depression - lightheadedness - confusion If you experience any of the following symptoms, call your doctor immediately: - skin rash - itching - difficulty breathing
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