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How should you take this medication?
The combination of acetaminophen, butalbital, and caffeine comes as a capsule and tablet to take by mouth. It usually is taken every 4 hours as needed. Follow the directions on your prescription label
carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take acetaminophen, butalbital, and caffeine exactly as directed. Do not take more than six tablets or capsules
in 1 day. If you think that you need more to relieve your symptoms, call your doctor.
This medication can be habit-forming. Do not take a larger dose, take it more often, or for a longer per
iod than your doctor tells you to.
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Missed Dose
Take the missed dose as soon as you remember. Do not takedouble dose of Esgic . Wait the prescribed amount of time before taking your next dose.
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Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For butalbital and acetaminophen combinat
ions, the following should be considered:
Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to butalbital or other barbiturates, or to acetaminophen, aspirin,
r caffeine. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
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Precautions while Using this Medicine
This medicine may cause some people to become drowsy, dizzy, or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangero
us if you are dizzy or are not alert and clearheaded.
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Significant Interactions:
It is especially important that your health care professional know if you are taking any of the following:
- Antidepressants, tricyclic (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendi
n], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [
e.g., Surmontil]) or
- Central nervous system (CNS) depressants (medicines that often cause drowsiness)¡XThese medicines may add to the effects of butalbital and increase the chance of drowsiness
or other side effects
- Divalproex (e.g., Depakote) or
- Valproic acid (e.g., Depakene)¡XThe chance of side effects may be increased
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Symptoms of overdose
Anxiety, confusion, excitement, irritability, nervousness, restlessness, or trouble in sleeping (severe, especially with products containing caffeine) ; convulsions (seizures) (for products containin
g caffeine); diarrhea, especially if occurring together with increased sweating, loss of appetite, and stomach cramps or pain; dizziness, lightheadedness, drowsiness, or weakness, (severe) ; freque
nt urination (for products containing caffeine) ; hallucinations (seeing, hearing, or feeling things that are not there); increased sensitivity to touch or pain (for products containing caffeine);
muscle trembling or twitching (for products containing caffeine); nausea or vomiting, sometimes with blood;
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