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Precautions Before Using This Medicine
Tricyclic antidepressants (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil
], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil])¡XHigher blood levels of these medicines may occur, which may increase the chance of developing unwante
effects. Your doctor may check the blood level of the tricyclic antidepressant, and may change the dose of either these medicines or Zoloft. Also, taking Zoloft with amitriptyline, clomipramine, or i
mipramine may increase the chance of developing the serotonin syndrome
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What is this medicine
Zoloft, an antidepressant (mood elevator), is used to treat depression, obsessive-compulsive disorders, and panic attacks.
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What side effects can this medication cause?
Less common or rare side effects may include:
- frequent urination, hair loss, heart attack, hemorrhoids, hiccups, high blood pressure, high pressure within the eye (glaucoma), hearing problems,
hot flushes, impotence, inability to stay seated, increased appetite, increased salivation, increased sex drive, inflamed nasal passages, inflammation of the penis, intolerance to light, irregular he
artbeat, itching, joint pains, kidney failure, lack of coordination, lack of sensation, leg cramps, menstrual problems, low blood pressure, migraine, movement problems,
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How to Use
Zoloft is available in capsule and oral concentrate forms. To prepare Zoloft oral concentrate, use the dropper provided. Measure out the amount of concentrate prescribed by your doctor and mix it with
4 ounces of water, ginger ale, lemon/lime soda, lemonade, or orange juice. (Do not mix the concentrate with any other type of beverage.) Drink the mixture immediately; do not prepare it in advance fo
r later use. At times, a slight haze may appear after mixing, but this is normal.
Improvement with Zoloft may not be seen for several days to a few weeks. You should expect to keep taking it
for at least several months.
Zoloft may make your mouth dry. For temporary relief suck a hard candy, chew gum, or melt bits of ice in your mouth.
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Adverse Effects
General: - Frequent: Asthenia. Infrequent: Malaise, generalized edema, rigors, weight decrease, weight increase. Rare: Enlarged abdomen, halitosis, otitis media, aphthous stomatitis.
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Overdosage
Human Experience:
There have been 3 cases of sertraline overdosage (approximately 4 to 10 times the maximum recommended daily dose). These 3 patients recovered completely without the need for spec
ific therapy
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